منابع مشابه
Autophagy.
Autophagy plays a direct or indirect role in health and disease. A simplified definition of autophagy is thatit is an exceedingly complex process which degrades modified, superfluous (surplus) or damaged cellularmacromolecules and whole organelles using hydrolytic enzymes in the lysosomes. It consists of sequentialsteps of induction of autophagy, formation of autophagosome precursor...
متن کاملAutophagy
For many conservationists, butterflies are some of the key species that can indicate the quality of an environment not only for themselves but for many other, often less visible, species. Some of their specific needs are often well known, but movements around their habitat and important factors within it are less understood. To help address this issue, a new study reports for the first time the...
متن کاملFinding Cells, Finding Molecules, Finding Patterns
Many modern molecular labelling techniques result in bright point signals. Signals from molecules that are detected directly inside a cell can be captured by fluorescence microscopy. Signals representing different types of molecules may be randomly distributed in the cells or show systematic patterns, indicating that the corresponding molecules have specific, non-random localisations and functi...
متن کاملAutophagy-monitoring and autophagy-deficient mice
Discovery of yeast autophagy-related (ATG) genes and subsequent identification of their homologs in other organisms have enabled researchers to investigate physiological functions of macroautophagy/autophagy using genetic techniques. Specific identification of autophagy-related structures is important to evaluate autophagic activity, and specific ablation of autophagy-related genes is a critica...
متن کاملCrosstalk Between Autophagy and Apoptosis in Heart Disease Autophagy in Ischemic Heart Disease Cardiomyocyte Autophagy in Load-Induced Heart Disease Autophagy and Atherosclerosis Molecular Mechanisms of Autophagy
Autophagy is a cell survival mechanism that involves degradation and recycling of cytoplasmic components, such as long-lived proteins and organelles. In addition, autophagy mediates cell death under specific circumstances. Apoptosis, a form of programmed cell death, has been well characterized, and the molecular events involved in apoptotic death are well understood. Damaged cardiomyocytes that...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Autophagy
سال: 2013
ISSN: 1554-8627,1554-8635
DOI: 10.4161/auto.23483